Lancet. 1979 Mar 3;1(8114):474-5.

Uptake of taurine by platelets in retinitis pigmentosa.

Airaksinen EM, Sihvola P, Airaksinen MM, Sihvola M, Tuovinen E.

Abstract

Uptake of 3H-taurine by platelets from twelve patients with retinitis pigmentosa (R.P.) and from healthy controls was measured. Platelets were incubated in autologous plasma with 3H-taurine for different times and at different substrate concentrations. The uptake of taurine by R.P. platelets at each incubation time was about two-thirds of the control value, the difference being statistically significant. Km was about the same, but Vmax was lower in R.P. platelets. The results suggest that R.P. is a disease affecting not only the eye but also taurine transport and/or storage in general.

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