The organization of internal telomeric repeats in the polytene chromosomes of the hypotrichous ciliate Stylonychia lemnae

S Stoll; T Zirlik; C Maercker; H J Lipps

doi:10.1093/nar/21.8.1783

The organization of internal telomeric repeats in the polytene chromosomes of the hypotrichous ciliate Stylonychia lemnae

Nucleic Acids Res. 1993 Apr 25;21(8):1783-8. doi: 10.1093/nar/21.8.1783.

Authors

S Stoll¹, T Zirlik, C Maercker, H J Lipps

Affiliation

¹ Medizinisch-Naturwissenschaftliches Forschungszentrum, Universität Tübingen, Germany.

Abstract

There exist about 1000-1500 internal telomeric sequences per haploid genome in the polytene chromosomes of the hypotrichous ciliate Stylonychia lemnae. All these telomeric repeats are contained in a very conserved element. This element consists of two 2 kb direct repeats flanking a 2.6 kb sequence. Immediately adjacent to one of the repeats a 18mer C4A4C4A4C2 telomeric sequence is localized. Sequences homologous to macronuclear DNA follow 180 bp downstream of the C4A4-bloc. These macronuclear homologous sequences are flanked by the second direct repeat. The possible origin and function of these telomere containing elements is discussed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Base Sequence
Chromosomes / ultrastructure*
DNA, Protozoan
Molecular Sequence Data
Repetitive Sequences, Nucleic Acid*
Restriction Mapping
Sequence Homology, Nucleic Acid
Sporadotrichina / genetics*
Sporadotrichina / ultrastructure
Telomere*

Substances

DNA, Protozoan