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    Genomics. 1993 Apr;16(1):286-8.

    Artificially generated data sets for testing DNA sequence assembly algorithms.

    Source

    Theoretical Biology and Biophysics Group, Los Alamos National Laboratory, New Mexico 87545.

    Abstract

    We have developed a set of tools, genfrag, to fragment and optionally mutate a DNA sequence to generate benchmark data sets for testing DNA sequence assembly algorithms. Data parameters can be systematically and independently varied to explore the range of data--and corresponding performance of assembly tools--encountered on large-scale random, or "shot-gun," sequencing projects.

    PMID:
    8486376
    [PubMed - indexed for MEDLINE]

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