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Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):90.

Treatment failure of a single high dose of ivermectin for Mansonella perstans filariasis.

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  • 1Institute for Tropical Medicine, Antwerp, Belgium.


Infections with Mansonella perstans are common in certain parts of Africa and South America. There is no standard treatment at present. We evaluated the effect of a single high dose of ivermectin (600 micrograms/kg) on microfilaraemia in 7 consecutive patients. No decrease in microfilarial counts could be demonstrated after a follow-up period of 7-56 d.

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