Abstract
Reading-frame corrective shifts in the nucleotide sequence upstream, within, or downstream from the putative coding region of several beta-glycanase-encoding genes reported in the literature reveal hidden active-site residues or even additional domains, including a cellulose-binding domain on a beta-mannanase-encoding gene. These findings also help in assigning, to cellulase family A, two enzymes previously found to lack sequence similarity with known cellulase families.
MeSH terms
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Amino Acid Sequence
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Bacteria / enzymology
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Bacteria / genetics
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Base Sequence
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Binding Sites
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Computer Simulation
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DNA, Bacterial
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Glycoside Hydrolases / genetics*
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Glycoside Hydrolases / metabolism
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Molecular Sequence Data
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Open Reading Frames
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Sequence Homology, Amino Acid
Substances
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DNA, Bacterial
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Glycoside Hydrolases
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glycanase
Associated data
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GENBANK/M20921
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GENBANK/M36063
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SWISSPROT/P04954
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SWISSPROT/P05522
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SWISSPROT/P06564
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SWISSPROT/P07982
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SWISSPROT/P07983
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SWISSPROT/P07984
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SWISSPROT/P07987
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SWISSPROT/P10474
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SWISSPROT/P10477
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SWISSPROT/P15704
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SWISSPROT/P17901
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SWISSPROT/P19424
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SWISSPROT/P19570
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SWISSPROT/P20847
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SWISSPROT/P22503
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SWISSPROT/P22699
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SWISSPROT/P23659