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Curr Opin Immunol. 1993 Feb;5(1):59-66.

Collectins: pattern recognition molecules involved in first line host defense.

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  • 1Department of Pathology, Boston University School of Medicine, Massachusetts 02118.

Erratum in

  • Curr Opin Immunol 1993 Aug;5(4):566.


A group of chimeric molecules comprising globular heads, which contain the carbohydrate recognition domain, and collagen tails are defined as collectins. The mannose-binding proteins, pulmonary surfactant apoproteins A and D and conglutinin all qualify as members of this family, whose function appears to be as pattern recognition molecules involved in the first line of defense in the pre-immune host.

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