Experientia. 1977 Feb 15;33(2):264-5.

Nitrate fertilizers as environmental pollutants: positive correlation between nitrates (NaNO3 and KNO3) used per unit area and stomach cancer mortality rates.

Abstract

Since a significant positive correlation between nitrate fertilizer exposure and stomach cancer mortality has been found, a study of nitrate fertilizer pollution in arable land in terms of amount of nitrates used per unit area (kg/ha) and stomach cancer death rates was carried out. The regression of death rates for stomach cancer, standardized for age, on the nitrates used per unit area, by province (N = 25), exhibited a significant association between the 2 variables (p less than 0.004). When industrialized provinceds (N = 3) were not considered, a highly significant association was found (F = 16.47; d.f. = 1, 20; p less than 0.0006). The correlation coefficient was + 0.672.

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Further evidence of a positive correlation between exposure to nitrate fertilizers (NaNO3 and KNO3) and gastric cancer death rates: nitrites and nitrosamines. [Experientia. 1975]
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Cited by 3 PubMed Central articles

Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment. [Proc Natl Acad Sci U S A. 1983]
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Wagner DA, Moldawer LL, Pomposelli JJ, Tannenbaum SR, Young VR. Biochem J. 1985 Dec 1; 232(2):547-51.
Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. [Proc Natl Acad Sci U S A. 1985]
Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.
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