Lipids. 1993 Feb;28(2):121-4.

Reduction of fatty acid hydroperoxides by human parotid saliva.

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National Food Research Institute, Ministry of Agriculture, Forestry and Fisheries, Ibaraki, Japan.

Abstract

Arachidonic acid hydroperoxide (15-hydroperoxyeicosatetraenoic acid; 15-HPETE) was introduced into human parotid saliva and incubated at 37 degrees C. Straight phase high-performance liquid chromatography analysis of the reaction mixture showed that 15-HPETE was detoxified to its reduced form, 15-hydroxyeicosatetraenoic acid, in the presence of glutathione. Therefore, it is concluded that human parotid saliva possesses fatty acid hydroperoxide-reducing ability. However, its effectiveness was found to be lower than that of blood plasma.

PMID:: 8441337; [PubMed - indexed for MEDLINE]

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Reduction of fatty acid hydroperoxides by human parotid saliva.

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