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1: Otolaryngol Clin North Am. 1993 Feb;26(1):23-35.Links

Actinic keratosis. A premalignant skin lesion.

Marks VJ.

Department of Dermatology, Geisinger Clinic, Danville, PA 17822.

The actinic keratotic lesion appearing on the sun-exposed skin of the middle-aged and elderly is a common premalignant lesion that infrequently becomes squamous cell carcinoma. Generally, superficially destructive measures provide adequate therapy for this epidermal dysplastic growth. Because of the rare threat of squamous cell carcinoma, a therapeutic dilemma results. If the physician detects any signs of malignancy, such as palpability, induration, or bleeding, a biopsy is mandatory for confirmation.

PMID: 8433840 [PubMed - indexed for MEDLINE]