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1: Cancer. 1993 Jan 15;71(2):354-8.Links

Acalculous cholecystitis in bone marrow transplant patients.

Jardines LA, O'Donnell MR, Johnson DL, Terz JJ, Forman SJ.

City of Hope National Medical Center, Duarte, California.

BACKGROUND. Acalculous cholecystitis (ACC) is an uncommon disorder of the biliary tract, accounting for approximately 6% of acute cholecystitis cases. In this study, cholecystitis was seen in 8 of 770 bone marrow transplant recipients, with ACC occurring in five (63%). METHODS. Records of 592 allogenic and 150 autologous BMT patients were reviewed for risk factors associated with ACC. RESULTS. Only the number of blood transfusions administered and the use of total parenteral nutrition were associated with ACC development. ACC occurred in 4 of 42 (9%) allogeneic recipients who required exchange transfusion for ABO incompatibility. ACC developed in one autogolous recipient alongside venoocclusive disease of the liver. There was no association between ACC development and preparative regimen, cyclosporine usage, graft versus host disease, or cytomegalovirus infection. CONCLUSIONS. ACC occurs more frequently in patients after ABO incompatible BMT requiring exchange transfusion than in other transplant recipients.

PMID: 8422628 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Cyclosporine (Neoral® , Sandimmune® , Gengraf® )

    Cyclosporine and cyclosporine (modified) are used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have rec...

  • Total Parenteral Nutrition

    Your doctor has ordered total parenteral nutrition (TPN) for you. TPN will drip through a needle or catheter placed in your vein for 10-12 hours, once a day or five times a week.

  • Source: AHFS Consumer Medication Information