Localization of indoleamine 2,3-dioxygenase gene (...[Cytogenet Cell Genet. 1993]

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1: Cytogenet Cell Genet. 1993;64(3-4):231-2.Links

Localization of indoleamine 2,3-dioxygenase gene (INDO) to chromosome 8p12-->p11 by fluorescent in situ hybridization.

Najfeld V, Menninger J, Muhleman D, Comings DE, Gupta SL.

Tumor Cytogenetics Laboratory, Mount Sinai Medical Center, New York, NY 10029.

Indolamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase are two enzymes that degrade tryptophan to N-formylkynurenine. The gene (TDO2) for tryptophane 2,3-dioxygenase has been localized to 4q31-->32. We now report localization of INDO (the gene encoding indolamine 2,3-dioxygenase) by fluorescent in situ hybridization to 8p12-->p11.

PMID: 8404046 [PubMed - indexed for MEDLINE]

ReviewThe human indoleamine 2,3-dioxygenase gene and related human genes. [Curr Drug Metab. 2007]
Localization of the human indoleamine 2,3-dioxygenase (IDO) gene to the pericentromeric region of human chromosome 8. [Genomics. 1993]
Assignment of the human indoleamine 2,3-dioxygenase gene to chromosome 8 using the polymerase chain reaction. [Hum Genet. 1994]
A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase. [Biochemistry. 2008]
ReviewA myoglobin evolved from indoleamine 2,3-dioxygenase, a tryptophan-degrading enzyme. [Comp Biochem Physiol B Biochem Mol Biol. 1998]

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Localization of indoleamine 2,3-dioxygenase gene (INDO) to chromosome 8p12-->p11 by fluorescent in situ hybridization.

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