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Cancer Genet Cytogenet. 1993 Jun;67(2):133-5.

Wilms' tumor in the Li-Fraumeni cancer family syndrome.

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  • 1CRC Paediatric & Familial Cancer Research Group, Christie Hospital NHS Trust, Manchester, U.K.


Scrutiny of the family pedigrees of a population-based series of 176 children diagnosed with Wilms' tumor between 1954 and 1990, along with a review of the literature on the Li-Fraumeni cancer family syndrome, indicate that Wilms' tumor may be an uncommon component of the syndrome and that a small proportion of children with Wilms' tumor may be members of Li-Fraumeni syndrome (LFS) families.

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