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Clin Neuropathol. 1993 May-Jun;12(3):153-5.

Adult onset nemaline myopathy: a distinct nosologic entity?

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  • 1Paolo Peirolo Centre for Neuromuscular Diseases, Universit√† di Torino, Italy.


A 61-year-old woman presented progressive distal weakness and wasting of her upper limbs spreading to the shoulder girdle and to the neck muscles. Creatine kinase, cerebrospinal fluid, spinal X-ray and spinal nuclear magnetic resonance were normal. Electromyography showed myopathic alterations. Muscle biopsy showed abundant rods in many fibres. Prednisone 75 mg/die for two months did not modify the symptoms.

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