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Oral Surg Oral Med Oral Pathol. 1993 Jun;75(6):690-5.

Hairy leukoplakia after bone marrow transplantation.

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  • 1Medical/Dental Staff, British Columbia Cancer Agency, Vancouver, Canada.


Hairy leukoplakia in 10 patients after bone marrow transplantation was identified clinically and assessed histologically. In situ hybridization for Epstein-Barr virus and human papilloma virus confirmed Epstein-Barr virus in hairy leukoplakia in two cases, and human papillomavirus in three cases. All cases with clinical follow-up resolved without treatment. These findings suggest that severe immunosuppression after a bone marrow transplantation may result in the development of hairy leukoplakia, and that as the immunosuppression resolves after the transplant the lesions also resolve.

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