Early pregnancy factor (EPF) as tumour marker in two patients with trophoblastic tumour

Arch Gynecol Obstet. 1993;252(4):215-8. doi: 10.1007/BF02426361.

Abstract

Two patients with a trophoblastic tumour (one with an invasive mole and one with a choriocarcinoma) had early pregnancy factor (EPF; detected by rosette inhibition test) in serum. In both cases the EPF already disappeared during surgery which suggests that EPF could be a useful and sensitive tumour marker if laboratory technology for its detection could be improved.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Missed / blood
  • Abortion, Missed / diagnosis
  • Adult
  • Biomarkers, Tumor / blood*
  • Chaperonin 10
  • Diagnosis, Differential
  • Female
  • Humans
  • Hydatidiform Mole / blood
  • Hydatidiform Mole / diagnosis
  • Middle Aged
  • Peptides / blood*
  • Pregnancy
  • Pregnancy Proteins*
  • Suppressor Factors, Immunologic*
  • Trophoblastic Neoplasms / blood
  • Trophoblastic Neoplasms / diagnosis*
  • Uterine Neoplasms / blood
  • Uterine Neoplasms / diagnosis*

Substances

  • Biomarkers, Tumor
  • Chaperonin 10
  • Peptides
  • Pregnancy Proteins
  • Suppressor Factors, Immunologic
  • early pregnancy factor