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Acta Obstet Gynecol Scand. 1993 May;72(4):310-3.

Blue rubber bleb nevus syndrome with manifestations in the vulva.

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  • 1Department of Gynecology and Obstetrics, Aker sykehus, Norway.


The blue rubber bleb nevus syndrome (BRBNS) is a rare vascular disorder, manifesting with hemangiomas which are usually located in the gastrointestinal tract and/or in the skin. These lesions can cause local, sometimes severe bleedings or cosmetic problems. This report describes a young woman with BRBNS manifestations on the buttocks and in the vulva, the latter giving rise to symptoms specific to this location. The blood-filled blebs were successfully treated by argon laser. As far as we know, manifestations of this disease in the female genital tract have not previously been described.

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