Detection of human papillomavirus DNA in an ameloblastoma using the in situ hybridization technique

W F van Heerden; E J van Rensburg; E J Raubenheimer; E H Venter

doi:10.1111/j.1600-0714.1993.tb01039.x

Detection of human papillomavirus DNA in an ameloblastoma using the in situ hybridization technique

J Oral Pathol Med. 1993 Mar;22(3):109-12. doi: 10.1111/j.1600-0714.1993.tb01039.x.

Authors

W F van Heerden¹, E J van Rensburg, E J Raubenheimer, E H Venter

Affiliation

¹ Department of Oral Pathology and Oral Biology, Medical University of Southern Africa, Medunsa.

PMID: 8387593
DOI: 10.1111/j.1600-0714.1993.tb01039.x

Abstract

HPV type 18 DNA was identified in an intrabony ameloblastoma using radiolabelled in situ hybridization. The viral DNA was found in a verrucous lesion in a cystic area of the tumor. The absence of HPV DNA in other epithelial areas of the ameloblastoma is suggestive of a secondary infection. HPV is not considered to be an etiological factor in the pathogenesis of this ameloblastoma.

Publication types

Case Reports

MeSH terms

Adult
Ameloblastoma / microbiology*
Ameloblastoma / pathology
DNA Probes, HPV
DNA, Viral / analysis*
DNA, Viral / genetics
Epithelium / pathology
Humans
Hyperplasia
Keratosis / pathology
Male
Mandibular Neoplasms / microbiology*
Mandibular Neoplasms / pathology
Nucleic Acid Hybridization
Papilloma / pathology
Papillomaviridae / genetics*

Substances

DNA Probes, HPV
DNA, Viral