Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Surg Oncol. 1993 Feb;52(2):77-82.

The effect of the fiber components cellulose and lignin on experimental colon neoplasia.

Author information

  • 1Department of Surgery, University of Kentucky College of Medicine, Lexington.

Abstract

Sixty Sprague-Dawley rats were pair-fed one of three nutritionally identical diets. One diet contained "low-fiber" (3.8% crude fiber); the others contained "high fiber" (28.7% crude fiber) composed of either cellulose or lignin. Although both "high fiber" diets had similar stool bulking effects, only the cellulose diet was associated with a reduction in 1,2-dimethylhydrazine (DMH)-induced colon neoplasms. The cellulose diet was also associated with distinct changes in the gut bacterial profile and with a lowered serum cholesterol.

PMID:
8385723
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk