Format

Send to:

Choose Destination
See comment in PubMed Commons below
Biochim Biophys Acta. 1993 Aug 19;1174(2):204-6.

Structure and deduced amino acid sequence of the human fibromodulin gene.

Author information

  • 1Department of Medical and Physiological Chemistry, University of Lund, Sweden.

Abstract

We have determined the structure and partially sequenced the human fibromodulin gene. The translated region of the gene is composed of two exons. An exon in the 5'-non translated region is separated from the next exon by a 1 kb intron. This exon, which encodes the major part of the translated region, is 983 bp and is followed by an approx. 5 kbp intron. The last 50 nucleotides of the translated region as well as the 3'-nontranslated region are located on the last exon. This exon arrangement is different from the arrangement reported for the gene of the structurally related biglycan. The translated region of the gene was sequenced and compared with bovine fibromodulin. The amino acid sequences of human and bovine fibromodulin show an overall homology of 90%.

PMID:
8357838
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk