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    Lancet. 1979 Jan 6;1(8106):17-9.

    Fetal damage despite low-phenylalanine diet after conception in a phenylketonuric woman.

    Abstract

    A woman with phenylketonuria gave birth to an infant with a cardiac defect and microcephaly despite introduction of a low-phenylalanine diet 5 weeks after conception (3 weeks after the first missed period). In maternal phenylketonuria fetal damage leading to reduced brain growth and cardiac malformations probably occurs within a few weeks of conception.

    PMID:
    83464
    [PubMed - indexed for MEDLINE]

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