[Supratentorial glioma: analysis of clinical and temporal parameters in 163 cases]

Neurochirurgia (Stuttg). 1993 Nov;36(6):189-93. doi: 10.1055/s-2008-1053826.
[Article in German]

Abstract

163 cases of supratentorial astrocytomas and glioblastomas were evaluated retrospectively after close-meshed observation and treatment. We attached the greatest importance to the reevaluation of already known prognostic parameters and to the temporal analysis of the course of gliomas. We could confirm the influence of the histologic grade on the survival time. Histologic grading by means of immunohistochemistry proved to be more precise than grading only by means of HE staining. Furthermore, the patient's age was one of the most important prognostic variables for survival time after operation. Other factors were the first preoperative Karnofsky rating, the preoperative diameter of the tumour, the duration of preoperative symptoms and the interval between operation and diagnosis of tumour recurrence as well as between tumour recurrence and reoperation. Epileptic seizures as preoperative symptoms were found to be far less prognostic for survival time. Localisation of the tumour, other preoperative symptoms, Karnofsky rating before reoperation and the extent of tumour resection proved to be of no importance for survival time.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Astrocytoma / mortality
  • Astrocytoma / pathology
  • Astrocytoma / surgery*
  • Child
  • Craniotomy
  • Female
  • Follow-Up Studies
  • Glioblastoma / mortality
  • Glioblastoma / pathology
  • Glioblastoma / surgery*
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / mortality
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery*
  • Neoplasm Staging
  • Postoperative Complications / mortality
  • Postoperative Complications / pathology
  • Postoperative Complications / surgery
  • Supratentorial Neoplasms / mortality
  • Supratentorial Neoplasms / pathology
  • Supratentorial Neoplasms / surgery*
  • Survival Rate