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Ned Tijdschr Geneeskd. 1994 Jan 15;138(3):145-8.

[Rapid cycling in bipolar disorders].

[Article in Dutch]

Author information

  • 1Psychiatrisch Ziekenhuis Endegeest, afd. Jelgersmapolikliniek, Oegstgeest.


Two patients, a woman aged 32 and a man aged 27 years, were suffering from rapid cycling bipolar disorder (i.e. a course with four or more episodes a year). Hypothyroidism and the use of antidepressants may be involved in the development of such a disease course. Treatment with carbamazepine was successful in both patients. Patients suffering from rapid cycling bipolar disorder should be treated with lithium or carbamazepine, or a combination of these. Antidepressants should only be used with great caution.

[PubMed - indexed for MEDLINE]
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