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J Biomed Eng. 1993 Nov;15(6):505-9.

Validation of an automated method of three-dimensional finite element modelling of bone.

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  • 1Rehabilitation Research & Development Service, Department of Veterans Affairs Medical Center, San Francisco, CA.


This study validated an automated method of finite element modelling of bone from CT scan data. After a fresh-frozen cadaveric femur was modelled, strain gauges were attached to the bone at 11 locations and the femur was mechanically tested by applying a load to the femoral head. Linear regression analysis was used to correlate the strains predicted by the model with the experimentally measured strains. The regression results were significant (P < 0.001), indicating that the strain calculated by the FE model is a valid predictor of the measured strain. Verification of the surface strains also supports the validity of the strains and stresses predicted inside the bone. The present study provides a strong rationale for use of this modelling method as a research tool and in possible clinical applications.

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