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Arch Neurol. 1994 Jan;51(1):90-4.

Dementia of adult polyglucosan body disease. Evidence of cortical and subcortical dysfunction.

Author information

  • 1Department of Neurology, University of Rochester, NY.

Abstract

OBJECTIVES:

To characterize the dementia associated with adult polyglucosan body disease (APBD) and to correlate the cognitive deficits with abnormalities found on magnetic resonance imaging (MRI).

METHODS:

Quantitative neuropsychological testing and MRI in one man with APBD and a review of the literature.

RESULTS:

The dementia of APBD affects cortical and subcortical functions. The cognitive deficits correlate with MRI findings of cortical atrophy and white-matter abnormalities.

CONCLUSION:

Neuropsychological testing and MRI are helpful in the evaluation of patients with APBD.

PMID:
8274116
[PubMed - indexed for MEDLINE]
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