The TYMV tRNA-like structure

Biochimie. 1993;75(7):569-82. doi: 10.1016/0300-9084(93)90063-x.

Abstract

The genomic RNA from turnip yellow mosaic virus presents a 3'-end functionally and structurally related to tRNAs. This report summarizes our knowledge about the peculiar structure of the tRNA-like domain and its interaction with tRNA specific proteins, like RNAse P, tRNA nucleotidyl-transferase, aminoacyl-tRNA synthetases, and elongation factors. It discusses also the biological role of this structure in the viral life cycle. A brief survey of our knowledge of other tRNA mimicries in biological systems, as well as their relevance for understanding canonical tRNA, will also be presented.

Publication types

  • Review

MeSH terms

  • Base Sequence
  • Molecular Sequence Data
  • Nucleic Acid Conformation*
  • RNA, Transfer / chemistry*
  • RNA, Transfer / metabolism
  • RNA, Viral / chemistry*
  • RNA, Viral / metabolism
  • Tymovirus / genetics*

Substances

  • RNA, Viral
  • RNA, Transfer