New antidepressants: use in high-risk patients. [J Clin Psychiatry. 1993]

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1: J Clin Psychiatry. 1993 Aug;54 Suppl:61-70; discussion 71-3.Links

New antidepressants: use in high-risk patients.

Hale AS.

Department of Academic Psychiatry, St. Thomas' Hospital, London, U.K.

This paper will review evidence on the safety and efficacy of new antidepressants in high-risk patients. Where available, data will be reviewed on the serotonin selective reuptake inhibitors (SSRIs), including fluoxetine, fluvoxamine, paroxetine, sertraline, and citalopram, and on the new reversible inhibitor of monoamine oxidase-A moclobemide.

PMID: 8253707 [PubMed - indexed for MEDLINE]

Review[Monoamine oxidase inhibitors in psychiatry. Status of current knowledge]
Nervenarzt. 1996 May; 67(5):339-47.

[Nervenarzt. 1996]
Efficacy and tolerability of moclobemide in comparison with placebo, tricyclic antidepressants, and selective serotonin reuptake inhibitors in elderly depressed patients: a clinical overview.
Can J Psychiatry. 1997 Dec; 42(10):1043-50.

[Can J Psychiatry. 1997]
ReviewMoclobemide. An update of its pharmacological properties and therapeutic use.
Drugs. 1996 Sep; 52(3):450-74.

[Drugs. 1996]
ReviewAcute therapy of depression.
J Clin Psychiatry. 1993 Aug; 54 Suppl:18-27; discussion 28.

[J Clin Psychiatry. 1993]
ReviewA risk-benefit assessment of moclobemide in the treatment of depressive disorders.
Drug Saf. 1995 Jan; 12(1):46-54.

[Drug Saf. 1995]
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Cited by 3 PubMed Central articles

ReviewTolerability and safety of fluvoxamine and other antidepressants.
Westenberg HG, Sandner C. Int J Clin Pract. 2006 Apr; 60(4):482-91.

[Int J Clin Pract. 2006]
Duloxetine for the long-term treatment of major depressive disorder in patients aged 65 and older: an open-label study.
Wohlreich MM, Mallinckrodt CH, Watkin JG, Hay DP. BMC Geriatr. 2004 Dec 7; 4:11. Epub 2004 Dec 7.

[BMC Geriatr. 2004]
Serotonin reuptake inhibitor, fluoxetine, dilates isolated skeletal muscle arterioles. Possible role of altered Ca2+ sensitivity.
Pacher P, Ungvari Z, Kecskemeti V, Koller A. Br J Pharmacol. 1999 Jun; 127(3):740-6.

[Br J Pharmacol. 1999]

Patient Drug Information

Fluoxetine (Prozac® , Prozac® Weekly, Sarafem® , ...)
Fluoxetine (Prozac) is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), some eating disorders, and panic attacks (sud...
Bupropion (Wellbutrin, Wellbutrin, Wellbutrin XL, ...)
How do the newer antidepressants compare in treating depression?
Escitalopram (Lexapro® )
Escitalopram is used to treat depression and generalized anxiety disorder (GAD; excessive worry and tension that disrupts daily life and lasts for 6 months or longer). Escitalopram is in a class of antidepressants called...
» See all 7 drug reports ...
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