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Localization of the human cholecystokinin-B/gastrin receptor gene (CCKBR) to chromosome 11p15.5-->p15.4 by fluorescence in situ hybridization.
Laboratory of Biology, National Cancer Institute, Besthesda, MD.
A human cholecystokinin-B/gastrin receptor cDNA (CCKBR) has been recently cloned and its transcriptional product has been characterized. The cDNA probe was mapped by fluorescence in situ hybridization to chromosome 11 at bands p15.5-->p15.4. The localization of this receptor gene provides a useful marker for this region of chromosome 11 permitting the identification of diseases involving the gene and interactions with other genes.
PMID: 8222757 [PubMed - indexed for MEDLINE]
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Cited by 4 PubMed Central articles
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Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver.
Sargent LM, Zhou X, Keck CL, Sanderson ND, Zimonjic DB, Popescu NC, Thorgeirsson SS.
Am J Pathol. 1999 Apr; 154(4):1047-55.
[Am J Pathol. 1999]
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Fluorescence in situ hybridization analysis of keratinocyte growth factor gene amplification and dispersion in evolution of great apes and humans.
Zimonjic DB, Kelley MJ, Rubin JS, Aaronson SA, Popescu NC.
Proc Natl Acad Sci U S A. 1997 Oct 14; 94(21):11461-5.
[Proc Natl Acad Sci U S A. 1997]
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Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.
Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin JS.
Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13):6770-5.
[Proc Natl Acad Sci U S A. 1997]
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