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Immunol Today. 1994 Mar;15(3):127-33.

CC chemokines in allergic inflammation.

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  • 1Theodor-Kocher Institute, University of Bern, Switzerland.


CC chemokines are small inducible proteins that are related to interleukin 8. Recent studies have shown that several CC chemokines, MCP-1, MCP-3, RANTES and MIP-1 alpha, act on basophils and/or eosinophils via GTP-binding protein-coupled receptors. Marco Baggiolini and Clemens Dahinden discuss the involvement of CC chemokines in the recruitment and activation of the main effector cells of allergic inflammation.

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