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Curr Opin Cell Biol. 1994 Feb;6(1):16-24.

Organization and function of the cytoskeleton in polarized epithelial cells: a component of the protein sorting machinery.

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  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, CA 94305-5426.

Abstract

Development and maintenance of cell-surface polarity in epithelial cells requires specialized localization of proteins to functionally and structurally distinct plasma membrane domains. The organization of these domains is dependent upon targeted delivery of transport vesicles between different membrane compartments, and upon protein sorting in the membranes of the Golgi complex and cell surface. Increasing evidence has been gathered in recent years that cytoskeletal components facilitate these processes.

PMID:
8167021
[PubMed - indexed for MEDLINE]
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