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    Nippon Rinsho. 1994 Mar;52(3):779-86.

    [Synthetic mineralocorticoid, clinical application of fludrocortisone acetate (Florinef)]

    [Article in Japanese]

    Igarashi Y.

    Department of Pediatrics, Hamamatsu University School of Medicine.

    Fludrocortisone acetate (Florinef), a 9 alpha-fluorinated derivative of hydrocortisone, has strong mineralocorticoid activity. From the calculated values in a tracer study, the divided dose regimen is recommended. Florinef has been widely used in the treatment of salt-wasting congenital adrenal hyperplasia (CAH). A tentative guideline for the treatment of salt-wasting CAH was described and its usefulness was discussed.

    PMID: 8164382 [PubMed - indexed for MEDLINE]

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    Patient drug information

    • Hydrocortisone Oral (Cortef®, Hydrocortone®)

      Hydrocortisone, a corticosteroid, is similar to a natural hormone produced by your adrenal glands. It is often used to replace this chemical when your body does not make enough of it. It relieves inflammation (swelling, ...

    • Fludrocortisone Acetate (Florinef® Acetate)

      Fludrocortisone, a corticosteroid, is used to help control the amount of sodium and fluids in your body. It is used to treat Addison's disease and syndromes where excessive amounts of sodium are lost in the urine. It wor...