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Trends Microbiol. 1993 Oct;1(7):255-60.

Helicobacter pylori: microbiology of a 'slow' bacterial infection.

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  • 1Dept of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2605.


The bacterium Helicobacter pylori lives in the gastric mucus layer of humans and induces a chronic inflammatory response that can result in both peptic ulceration and gastric neoplasms. Helicobacter pylori infection can be considered as a 'slow', adaptive and autoregulating process. The mechanisms by which this slow bacterial pathogen survives and interacts with the host immune system may provide a model for other persistent mucosal pathogens.

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