Receptor. 1993 Winter;3(4):325-41.

Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).

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Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.

Abstract

Models of the lectin-homology domains of the human and murine low-affinity receptors for IgE (Fc epsilon RII/CD23) were built on the basis of sequence similarity with rat mannose-binding protein, the structure of which is known. The sites on Fc epsilon RII/CD23 that are possibly involved in the interaction with IgE and with another ligand, CD21/CR2, are proposed. The models may assist the design of protein engineering experiments for the study of the reactivity of these molecules.

PMID:: 8142907; [PubMed - indexed for MEDLINE]

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The oligomeric nature of the murine Fc epsilon RII/CD23. Implications for function. [J Immunol. 1993]
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Dierks SE, Bartlett WC, Edmeades RL, Gould HJ, Rao M, Conrad DH. J Immunol. 1993 Mar 15; 150(6):2372-82.
Binding site for IgE of the human lymphocyte low-affinity Fc epsilon receptor (Fc epsilon RII/CD23) is confined to the domain homologous with animal lectins. [Proc Natl Acad Sci U S A. 1989]
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Bettler B, Maier R, Rüegg D, Hofstetter H. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):7118-22.
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Gould H, Sutton B, Edmeades R, Beavil A. Monogr Allergy. 1991; 29:28-49.
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Review Low affinity IgE receptors: regulation and functional roles in cell activation.
Yodoi J, Hosoda M, Maeda Y, Sato S, Takami M, Kawabe T. Ciba Found Symp. 1989; 147:133-48; discussion 148-52.

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Cited by 3 PubMed Central articles

The structure of human CD23 and its interactions with IgE and CD21. [J Exp Med. 2005]
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Hibbert RG, Teriete P, Grundy GJ, Beavil RL, Reljic R, Holers VM, Hannan JP, Sutton BJ, Gould HJ, McDonnell JM. J Exp Med. 2005 Sep 19; 202(6):751-60.
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Structure-based modeling of the ligand binding domain of the human cell surface receptor CD23 and comparison of two independently derived molecular models. [Protein Sci. 1996]
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Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).
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Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).

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