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Cornea. 1994 Jan;13(1):80-1.

Bilateral keratoconus in Crouzon's syndrome.

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  • 1Department of Ophthalmology, New York Medical College, Westchester County Medical Center, Valhalla 10595.


Crouzon's syndrome is an autosomal dominant disorder characterized by premature craniosynostosis leading to multiple ocular abnormalities and vision loss. Strabismus, optic atrophy, exposure keratitis, hypertelorism, nystagmus, and unexplained visual loss have been reported. Keratoconus has been described only once previously in a patient with other ocular abnormalities. This article reports bilateral keratoconus in a patient with Crouzon's syndrome without other ocular pathology. We emphasize the importance of early recognition and therapy of this treatable cause of decreased vision in Crouzon's syndrome.

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