Mamm Genome. 1993 Sep;4(9):499-503.

The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor (Cchl1a3 = mdg) maps to mouse chromosome 1 and human 1q32.

Drouet B, Garcia L, Simon-Chazottes D, Mattei MG, Guénet JL, Schwartz A, Varadi G, Pinçon-Raymond M.

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Groupe de Biologie, Développement et Régénération du Système Neuromusculaire, INSERM U. 153, Paris, France.

Abstract

Using both chromosomal in situ hybridization and molecular techniques, we report the genetic localization of the gene coding for the alpha 1 subunit of the skeletal slow Ca2+ current channel/DHP receptor gene (Cchl1a3) on human Chromosome (Chr) 1 (1q31-1q32 region) and on mouse Chr 1 (region (F-G)). On the basis of single-strand conformation polymorphism (SSCP-PCR) analysis in an interspecific backcross, we have determined that the Cchl1a3 = mdg (muscular dysgenesis) locus is very closely linked to the myogenin (Myog) locus.

PMID:: 8118099; [PubMed - indexed for MEDLINE]

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The gene for the alpha 1 subunit of the skeletal muscle dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse chromosome 1. [Genomics. 1992]
The gene for the alpha 1 subunit of the skeletal muscle dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse chromosome 1.
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Review [Molecular genetics of cardiovascular calcium channels]. [Arch Mal Coeur Vaiss. 1997]
Review [Molecular genetics of cardiovascular calcium channels].
Lory P, Monteil A, Nargeot J. Arch Mal Coeur Vaiss. 1997 Jun; 90 Spec No 3:17-24.

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Cited by 2 PubMed Central articles

DHPR alpha1S subunit controls skeletal muscle mass and morphogenesis. [EMBO J. 2010]
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The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor...
The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor (Cchl1a3 = mdg) maps to mouse chromosome 1 and human 1q32.
Mamm Genome. 1993 Sep ;4(9):499-503.

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The gene coding for the alpha 1 subunit of the skeletal dihydropyridine receptor (Cchl1a3 = mdg) maps to mouse chromosome 1 and human 1q32.

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