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    Ann Biomed Eng. 1993 Nov-Dec;21(6):727-33.

    Elastic modulus of prepared canine jejunum, a new vascular graft material.

    Herbert ST, Badylak SF, Geddes LA, Hillberry B, Lantz GC, Kokini K.

    William A. Hillenbrand Biomedical Engineering Center, Purdue University, West Lafayette, IN 47907.

    The submucosal connective tissue of the jejunum has been shown to be suitable for use as a vascular graft in preliminary dog studies. To partially characterize the mechanical properties of this new graft material, longitudinal stress (sigma)-strain (epsilon)-data were obtained on 13 specimens of canine jejunum, stripped of its mucosal and external smooth-muscle layers. The ratio of stress to strain is the modulus of elasticity (E). It was found that the stress sigma-strain epsilon-data fitted the expression sigma = K epsilon alpha very well. For a typical specimen sigma = 2.69 x 10(6) epsilon 2.33. The modulus of elasticity (E = sigma 1-1/alpha K1/alpha) was found to increase with increasing stress, ranging from about 2,000 to 9,000 mmHg. For the average specimen E = 573 sigma 0.57, where sigma is in mmHg, (1 mmHg = 133.3 Pascals).

    PMID: 8116923 [PubMed - indexed for MEDLINE]

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