Format

Send to:

Choose Destination
See comment in PubMed Commons below
JAMA. 1994 Mar 9;271(10):751-4.

Reduction of bacteriuria and pyuria after ingestion of cranberry juice.

Author information

  • 1Program for the Analysis of Clinical Strategies, Brigham and Women's Hospital, Boston, MA 02115.

Abstract

OBJECTIVE:

To determine the effect of regular intake of cranberry juice beverage on bacteriuria and pyuria in elderly women.

DESIGN:

Randomized, double-blind, placebo-controlled trial.

SUBJECTS:

Volunteer sample of 153 elderly women (mean age, 78.5 years).

INTERVENTION:

Subjects were randomly assigned to consume 300 mL per day of a commercially available standard cranberry beverage or a specially prepared synthetic placebo drink that was indistinguishable in taste, appearance, and vitamin C content but lacked cranberry content.

OUTCOME MEASURES:

A baseline urine sample and six clean-voided study urine samples were collected at approximately 1-month intervals and tested quantitatively for bacteriuria and the presence of white blood cells.

RESULTS:

Subjects randomized to the cranberry beverage had odds of bacteriuria (defined as organisms numbering > or = 10(5)/mL) with pyuria that were only 42% of the odds in the control group (P = .004). Their odds of remaining bacteriuric-pyuric, given that they were bacteriuric-pyuric in the previous month, were only 27% of the odds in the control group (P = .006).

CONCLUSIONS:

These findings suggest that use of a cranberry beverage reduces the frequency of bacteriuria with pyuria in older women. Prevalent beliefs about the effects of cranberry juice on the urinary tract may have microbiologic justification.

PMID:
8093138
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems
    Loading ...
    Write to the Help Desk