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Int Arch Allergy Immunol. 1994 Sep;105(1):56-61.

Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects.

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  • 1Central Laboratory of The Netherlands, Red Cross Blood Transfusion Service, Amsterdam.


A monoclonal antibody to Dermatophagoides pteronyssinus is described that cross-reacts with an IgE-binding antigen present in insects, Crustacea (e.g. shrimp) and other invertebrates. By means of sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gel filtration and immunofluorescence it was shown that this monoclonal antibody presumably recognizes tropomyosin. Tropomyosin was shown to be involved in cross-reactivity between mite, shrimp and insects in shrimp-allergic patients.

[PubMed - indexed for MEDLINE]
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