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Chest. 1994 Sep;106(3):965-7.

Localized pleural mesothelioma with elevation of high molecular weight insulin-like growth factor II and hypoglycemia.

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  • 1Division of Pulmonary Medicine, University of Tsukuba, Ibaraki, Japan.

Abstract

Recurrent hypoglycemia occurred in a 48-year-old woman with a localized pleural mesothelioma. During hypoglycemia, serum high molecular weight insulin-like growth factor II (IGF-II) was elevated. The tumor also contained a high level of high molecular weight IGF-II. We propose that the primary cause of the hypoglycemia in this patient was the high molecular weight IGF-II produced by the tumor.

PMID:
8082393
[PubMed - indexed for MEDLINE]
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