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Natl Med J India. 1994 May-Jun;7(3):119-22.

Intradermal rabies immunization for pre- and post-exposure prophylaxis.

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  • 1Centre for Tropical Medicine, John Radcliffe Hospital, Oxford, United Kingdom.


Human diploid cell rabies vaccine and similar tissue culture-produced vaccines are too expensive for widespread use in India, but alternative regimes can reduce the cost of post-exposure treatment by 60%. Multiple-site intradermal injections of tissue culture vaccine have proved effective, economical and safe. As these vaccines are becoming more freely available, the intradermal method can now be used to accelerate the replacement of nervous tissue vaccines.

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