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    Acta Anaesthesiol Scand. 1994 May;38(4):328-35.

    The effect of balanced analgesia on early convalescence after major orthopaedic surgery.

    Møiniche S, Hjortsø NC, Hansen BL, Dahl JB, Rosenberg J, Gebuhr P, Kehlet H.

    Department of Anaesthesiology, Hvidovre University Hospital, Copenhagen, Denmark.

    Forty-two patients scheduled for total knee arthroplasty (n = 20) or hip arthroplasty (n = 22) were randomly allocated to receive either continuous epidural bupivacaine/morphine for 48 h postoperatively plus oral piroxicam, or general anaesthesia followed by a conventional intramuscular opioid and acetaminophen regimen. Patients undergoing knee- or hip arthroplasty treated with epidural analgesia had significantly lower pain scores during mobilization under the 48 h epidural infusion compared with patients receiving conventional treatment, while no important differences were observed after cessation of the epidural regimen. However, the achieved pain relief had no impact on postoperative convalescence parameters, such as ambulation, patient activity including need for nursing care, fatigue or hospital stay. Late postoperative pain, fatigue and conservative attitudes and routines in the postoperative care, were the most important reasons limiting mobilization and activity. We conclude that effective early (48 h) postoperative pain relief with balanced analgesia does not per se lead to important improvements in convalescence and hospital stay.

    PMID: 8067218 [PubMed - indexed for MEDLINE]

    Supplemental Content

    Patient drug information

    • Acetaminophen (Acephen®, Anacin® Aspirin Free Maximum Strength Tablets®, Capital® and Codeine, ...)

      Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever. Acetamino...

    • Piroxicam (Feldene®)

      Piroxicam is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the ...

    • Morphine Oral (Avinza®, Kadian®, MS Contin®, ...)

      Morphine is used to relieve moderate to severe pain. Morphine long-acting tablets and capsules are only used by patients who are expected to need medication to relieve moderate to severe pain around-the-clock for longer ...