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Tsitol Genet. 1993 Nov-Dec;27(6):97-104.

[The immunological manifestations and cytological characteristics of infection caused by the simian immunodeficiency virus (SIV) in rhesus monkeys].

[Article in Russian]


The results of immunological and morphological studies of Asian macaques (Macaca mulatta) infected by simian immunodeficiency virus (SIV) are summarized in this review of literature. This virus causes development of the immunodeficiency disease that closely resembles human AIDS. Immunological parameters (CD count, antibody response etc.) are described promoting prediction of progression of immunodeficiency in monkeys. The morphological features of injury of internal organs indicate that SIV-induced immunodeficiency is the multisystem disease.

[PubMed - indexed for MEDLINE]
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