Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Nature. 1994 Aug 25;370(6491):621-8.

Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria.

Author information

  • 1Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

Abstract

In the crystal structure of bovine mitochondrial F1-ATPase determined at 2.8 A resolution, the three catalytic beta-subunits differ in conformation and in the bound nucleotide. The structure supports a catalytic mechanism in intact ATP synthase in which the three catalytic subunits are in different states of the catalytic cycle at any instant. Interconversion of the states may be achieved by rotation of the alpha 3 beta 3 subassembly relative to an alpha-helical domain of the gamma-subunit.

Comment in

PMID:
8065448
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk