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    Biochim Biophys Acta. 1994 Aug 11;1223(1):155-9.

    Human N-methyl-D-aspartate receptor modulatory subunit hNR2A: cloning and sequencing of the cDNA and primary structure of the protein.

    Source

    Allelix Biopharmaceuticals Inc., Mississauga, Ontario, Canada.

    Abstract

    Several cDNA clones encoding the human N-methyl-D-aspartate receptor modulatory subunit hNR2A, were isolated from human hippocampus and fetal brain libraries. DNA sequence analysis revealed overlapping clones permitting the reconstruction of full-length hNR2A cDNA. The hNR2A cDNA demonstrated an 88-89% nucleotide (nt) identity with the corresponding rodent cDNAs. The nt sequence of hNR2A would encode a 1464-aa protein that has a 95.2% identity with the rodent NR2A subunits.

    PMID:
    8061049
    [PubMed - indexed for MEDLINE]

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