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Cloning and sequence analysis of the human SNAP25 cDNA.
Human Genome Center, University of Tokyo, Japan.
During the screening of human brain-specific cDNAs by a modified differential hybridization analysis, we found a clone which was highly and specifically expressed in the (adult) brain. This clone was subjected to nucleotide sequence analysis and proven to be a nearly full-length cDNA of a human homologue of the previously reported mouse synaptosomal-associated protein 25 (mSNAP25). The human SNAP25 (hSNAP25) and mSNAP25 showed perfect amino-acid sequence conservation.
PMID: 8056350 [PubMed - indexed for MEDLINE]
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Cited by 3 PubMed Central articles
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Target genes of neuron-restrictive silencer factor are abnormally up-regulated in human myotilinopathy.
Barrachina M, Moreno J, Juvés S, Moreno D, Olivé M, Ferrer I.
Am J Pathol. 2007 Oct; 171(4):1312-23. Epub 2007 Sep 6.
[Am J Pathol. 2007]
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A Huntington disease-like neurodegenerative disorder maps to chromosome 20p.
Xiang F, Almqvist EW, Huq M, Lundin A, Hayden MR, Edström L, Anvret M, Zhang Z.
Am J Hum Genet. 1998 Nov; 63(5):1431-8.
[Am J Hum Genet. 1998]
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Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.
Jagadish MN, Fernandez CS, Hewish DR, Macaulay SL, Gough KH, Grusovin J, Verkuylen A, Cosgrove L, Alafaci A, Frenkel MJ, et al.
Biochem J. 1996 Aug 1; 317 ( Pt 3):945-54.
[Biochem J. 1996]