Biochem Biophys Res Commun. 1994 Jul 29;202(2):1009-14.

cDNA cloning of human kidney pyruvate carboxylase.

MacKay N, Rigat B, Douglas C, Chen HS, Robinson BH.

Source

Department of Biochemistry, University of Toronto, Ontario, Canada.

Abstract

cDNA clones covering a total of 4017 bp were isolated corresponding to the full length of the message for human pyruvate carboxylase. The coding sequence consisted of a stretch of 3534 bp flanked by a 5' untranslated sequence of 82 bp and a 3' untranslated region of 389 bp excluding the poly-A tail. The translated amino acid sequence of 1178 residues contained consensus sequences for the covalent attachment for biotin, the binding of ATP and the binding of the substrate, pyruvate.

PMID:: 8048912; [PubMed - indexed for MEDLINE]

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Research Support, Non-U.S. Gov't

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GENBANK/S72370

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Cited by 4 PubMed Central articles

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