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1: J Neuroophthalmol. 1994 Mar;14(1):2-5.Links

Isolated fascicular abducens nerve palsy and Lyme disease.

Mastrianni JA, Galetta SL, Raps EC, Liu GT, Volpe NJ.

Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia 19104.

A patient with Lyme disease developed an isolated sixth nerve palsy at the end of a 1 month course of oral antibiotics. Magnetic resonance imaging disclosed high-signal abnormality at the left pontomedullary junction, implicating involvement of the distal sixth nerve fascicle. Although facial numbness ensued during a subsequent course of intravenous antibiotics, corticosteroid therapy was associated with prompt improvement of neurologic signs, suggesting an immunologic mechanism for the central nervous system dysfunction.

PMID: 8032474 [PubMed - indexed for MEDLINE]