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Biochim Biophys Acta. 1994 Jun 21;1218(2):225-8.

A novel serine proteinase-like sequence from human brain.

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  • 1Department of Biochemistry, University of Basel, Switzerland.


From Alzheimer's visual cortex mRNA, a novel cDNA sequence with homology to the carboxy-terminal two-thirds of known serine proteinases was isolated (43% identity with human trypsinogen II). The corresponding mRNA has a size of approximately 8 kb and is expressed in low amounts in all human tissues tested.

[PubMed - indexed for MEDLINE]
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