Format

Send to:

Choose Destination
See comment in PubMed Commons below
Br Heart J. 1994 May;71(5):408-12.

Coronary artery surgery in women compared with men: analysis of coronary risk factors and in-hospital mortality in a single centre.

Author information

  • 1Cardiac Surgical Unit, Harefield Hospital, Middlesex.

Abstract

OBJECTIVE:

To determine differences in coronary risk factors between women and men and their relation to in-hospital mortality associated with coronary artery bypass grafting.

DESIGN:

Prospective observational study.

SETTING:

A regional cardiothoracic centre.

PATIENTS:

482 (362 (75%) men and 120 (25%) women) consecutive patients who had primary isolated coronary artery bypass grafting.

RESULTS:

The women were on average three years older than the men (63 v 60 years, P < 0.001). Women more frequently had hypertension (47% v 33%, P < 0.01), diabetes mellitus (21% v 10%, P < 0.005), hypothyroidism (9% v 2%, P < 0.003), and a family history of premature coronary heart disease (49% v 31%, P < 0.0006). More of the men were cigarette smokers (67% v 45%, P > 0.00001). Many of the women and men had dyslipidaemia. Postmenopausal women had a higher concentration of serum total cholesterol than men of a comparable age, (7.3 mmol/l v 6.5 mmol/l, P = 0.0002). Although arterial grafts were often used in both sexes, they were more often used in men than in women (91% v 78% respectively, P = 0.0003). In-hospital mortality was 2.1% (1.4% in men and 4.2% in women, P = 0.14). The estimated one year probability of survival in men who had survived 30 days was 0.99 with 95% confidence interval 0.98 to approximately 1 while that for women was 0.97 with 95% confidence interval 0.91 to approximately 1. Univariate analysis showed that preoperative history of diabetes mellitus was a predictor of mortality (P = 0.03).

CONCLUSION:

There were differences in the incidence and type of risk factors in men and women who had coronary artery bypass grafting. Preoperative diabetes mellitus was a predictor of in-hospital mortality.

PMID:
8011402
[PubMed - indexed for MEDLINE]
PMCID:
PMC483714
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk