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    Dig Dis Sci. 1994 Dec;39(12 Suppl):101S-103S.

    Measurement of gastric emptying and gastric motility by magnetic resonance imaging (MRI).

    Source

    Division of Gastroenterology, University Hospital, Zurich, Switzerland.

    Abstract

    Hitherto it has been impossible to measure noninvasively gastric emptying and motility from multiple regions of the stomach in humans. We describe the development of a novel methodology to achieve this using magnetic resonance imaging (MRI). Initial validation studies performed in five healthy volunteers demonstrated similar gastric emptying curves and secretion rates after ingestion of 10% dextrose labeled with [Gd]DOTA, assessed by MRI ([Gd]DOTA as meal marker) and a simultaneous double-indicator technique. Comparison between MRI and scintigraphy in five patients also gave similar results. Application of newer MRI technology allowing a series of coronal scans 1.2 sec apart permitted quantification of wall motion in the proximal and distal stomach in seven healthy volunteers. These results indicate that MRI provides new insights into the mechanisms responsible for both normal and disordered emptying.

    PMID:
    7995199
    [PubMed - indexed for MEDLINE]

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