Large cell, calcifying, Sertoli cell tumour, because of its distinct pathological and clinical presentations, has recently been recognized as a variant of Sertoli cell tumour. A 26-year-old man with this tumour is described, with a 3-year follow-up. Large cell, calcifying, Sertoli cell tumours occur mostly in young people. At least 6 of the 14 cases reported in the literature were associated with endocrine disorders or cardiac myxoma, or both. The patient described in this report had no endocrine or other disorders.